When you need a dinner that delivers bold flavor and creamy comfort, this Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce is the answer. The perfectly seared Cajun-spiced chicken packs a flavorful punch, while tender bowtie pasta gets coated in a rich, silky cheese sauce that melts right into every fold and ridge. It’s hearty enough for a cozy night in but also impressive enough to serve guests.

This dish brings together the smoky heat of Cajun seasoning, the mild stretch of mozzarella, and the buttery smoothness of cream for a truly indulgent finish. You’ll love how easily it comes together with pantry-friendly ingredients and just one pan for the sauce—making cleanup a breeze, too.

What Kind of Pasta Works Best for Creamy Cajun Chicken?

Bowtie pasta (also known as farfalle) is the star here for a reason. Its unique shape holds onto the sauce beautifully and gives every bite a satisfying texture. However, penne or rotini could work in a pinch if needed—just make sure to cook al dente so the pasta doesn’t lose its bite against the creamy sauce.

Ingredients for the Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce

Chicken breasts or tenders: Boneless and skinless chicken pieces absorb the Cajun spice beautifully and sear to juicy perfection.

Cajun seasoning: The backbone of the flavor, bringing spice, smokiness, and depth. Make your own or use your favorite store-bought blend.

Butter and olive oil: A mix of fats gives the chicken a golden crust and forms the base of the sauce.

Heavy cream: Essential for a rich, velvety texture in the cheese sauce.

Mozzarella cheese: Provides gooey meltiness and a mild, milky flavor that balances the spice.

Garlic: Adds warmth and depth to the sauce.

Parmesan cheese: Boosts the cheesy richness and adds a salty edge.

Bowtie pasta: The perfect shape to cradle the creamy sauce.

Salt and pepper: To season the chicken and balance the sauce.

Fresh parsley: For garnish and a burst of color to finish the plate.

How To Make the Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce

Step 1: Season and Sear the Chicken

Generously coat your chicken breasts or tenders with Cajun seasoning, salt, and pepper. Heat a mix of butter and olive oil in a large skillet over medium-high heat. Cook the chicken for 4–5 minutes per side, or until golden brown and cooked through. Remove from pan and let rest.

Step 2: Cook the Bowtie Pasta

While the chicken is cooking, boil the bowtie pasta in salted water according to package directions. Drain and set aside, reserving a little pasta water in case the sauce needs thinning.

Step 3: Make the Creamy Mozzarella Sauce

In the same skillet used for the chicken, add a bit more butter and sauté minced garlic for 1 minute. Pour in heavy cream and bring to a low simmer. Stir in mozzarella and parmesan until melted and smooth. Add salt and pepper to taste.

Step 4: Combine Pasta and Sauce

Add the cooked bowtie pasta to the skillet, tossing to coat with the creamy cheese sauce. If the sauce is too thick, add a splash of pasta water to loosen it up.

Step 5: Slice Chicken and Serve

Slice the rested Cajun chicken and arrange over the creamy pasta. Sprinkle fresh chopped parsley on top and serve warm.

How to Serve and Store This Creamy Cajun Chicken Pasta

This pasta is best served hot right after cooking, when the cheese sauce is velvety and the chicken still juicy. It pairs wonderfully with a crisp green salad or roasted vegetables.

To store leftovers, let the dish cool completely and refrigerate in an airtight container for up to 3 days. Reheat gently on the stovetop or microwave, adding a splash of cream or milk to revive the sauce’s creaminess.

Frequently Asked Questions

Can I use pre-cooked chicken?

Yes, though for maximum flavor, searing raw seasoned chicken is best. If using rotisserie or leftovers, toss with Cajun seasoning before adding.

Can I make this dish less spicy?

Absolutely. Use less Cajun seasoning or choose a mild blend. You can also add more cream or cheese to mellow the heat.

What can I substitute for heavy cream?

You can use half-and-half or whole milk, but the sauce won’t be as rich. Consider adding a bit more cheese to thicken.

Will other cheeses work?

Mozzarella melts best, but Monterey Jack or Fontina could also work well.

Can I freeze this pasta?

Cream-based sauces don’t always freeze well—they can split when reheated. It’s best enjoyed fresh or refrigerated.

How can I make it gluten-free?

Use gluten-free pasta and ensure your Cajun seasoning doesn’t contain flour.

Want More Pasta Ideas with a Twist?

If this Bowtie Pasta with Creamy Cajun Chicken hit the spot, you might also love these creative pasta favorites:

📌 Save this recipe to your Pinterest dinner board so you can revisit this creamy comfort dish anytime.

And I want to hear your take! Did you make it spicier? Try it with shrimp? Drop your version in the comments below.

Your creativity and feedback help everyone enjoy dinner more. Let’s inspire each other!

Find more dinner inspiration on my Pinterest: Life with Jam

Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce

Author: Jam Scott
Total Time: 30 minutes
Yield: 4 servings

Print Recipe

Description

A creamy, comforting pasta dish that combines Cajun-spiced chicken with a luscious mozzarella and parmesan cheese sauce, all tossed with tender bowtie pasta. Perfect for cozy dinners or entertaining guests.

Instructions

1. Season chicken with Cajun seasoning, salt, and pepper. Sear in butter and olive oil over medium-high heat for 4–5 minutes per side. Remove and rest.

2. Cook bowtie pasta in salted boiling water until al dente. Drain, reserving ½ cup pasta water.

3. In the same pan, sauté garlic in butter. Add cream and simmer. Stir in mozzarella and parmesan until melted. Season to taste.

4. Toss pasta into sauce. Loosen with pasta water if needed.

5. Slice chicken and serve over pasta. Garnish with fresh parsley.