Name: Cajun Chicken Bites with Creamy Garlic Herb Alfredo Twists
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: Cajun-Inspired
Ingredients: 2 large chicken breasts, cubed; 1 ½ tablespoons Cajun seasoning; 1 tablespoon olive oil; 2 tablespoons butter, divided; 3 cloves garlic, minced; 1 cup heavy cream; ¾ cup grated Parmesan cheese; 2 tablespoons chopped fresh parsley; 1 tablespoon chopped fresh dill; 8 ounces rotini pasta; Salt and pepper, to taste

Juicy, golden Cajun chicken bites meet twirls of creamy garlic herb Alfredo pasta in this weeknight-friendly stunner that looks like it took hours. This recipe is a flavor bomb—smoky heat from the Cajun spices, creamy richness from the Alfredo sauce, and fresh herbs to round it all out. Perfect for dinner guests or meal prep, it’s satisfying without being heavy.

One skillet for the chicken, one pot for the pasta, and a plateful of comfort when you’re done. Whether you like your chicken with a kick or want a mellow creamy twist to balance it, this dish gives you both in every bite. Add a touch of fresh dill or parsley on top for a bright herbal contrast that makes it sing.

What Kind of Cajun Seasoning Should I Use?

A homemade Cajun spice mix gives you full control, but a quality store-bought blend works perfectly too. Look for one that balances paprika, garlic powder, onion powder, oregano, thyme, and cayenne. If yours leans salty, scale back on added salt to the chicken. For a milder take, dial down the cayenne or mix with smoked paprika for flavor without fire.

Ingredients for the Cajun Chicken Bites with Creamy Garlic Herb Alfredo Twists

Chicken breast: Lean, juicy, and quick to cook. Chicken breast is the protein anchor and takes on Cajun seasoning beautifully.
Cajun seasoning: Brings smoky, spicy depth to the chicken. Adjust heat level to taste.
Olive oil: Helps sear the chicken to golden perfection without drying it out.
Butter: Adds richness to both the chicken and the Alfredo sauce.
Garlic: The aromatic backbone for the Alfredo sauce. Use fresh for best flavor.
Heavy cream: The base of that dreamy Alfredo. Provides silky, luxurious texture.
Parmesan cheese: For classic Alfredo flavor and a bit of salty, umami bite.
Fresh herbs (parsley, dill): Brighten up the creamy pasta and give a fresh finish.
Rotini pasta: The spirals hold the sauce beautifully and keep each bite flavorful.
Salt & pepper: Essential for seasoning throughout.

How To Make the Cajun Chicken Bites with Creamy Garlic Herb Alfredo Twists

Step 1: Prep and Season the Chicken

Cube your chicken breasts into bite-sized pieces. Toss them in a generous amount of Cajun seasoning, ensuring each piece is well coated. Let them sit while you prep the rest—this lets the spices soak in.

Step 2: Sear the Chicken

Heat olive oil and a touch of butter in a large skillet over medium-high heat. Add the seasoned chicken in a single layer. Cook for 5-7 minutes, turning occasionally, until browned and cooked through. Set aside and keep warm.

Step 3: Boil the Pasta

While the chicken cooks, bring a large pot of salted water to a boil. Cook the rotini pasta according to package instructions until al dente. Drain and set aside.

Step 4: Make the Alfredo Sauce

In the same skillet you used for the chicken, reduce the heat to medium. Add butter and minced garlic, sautéing for 1-2 minutes until fragrant. Pour in the heavy cream, bring it to a gentle simmer, and stir in the grated Parmesan. Let the sauce thicken slightly, about 3-5 minutes.

Step 5: Toss Pasta in the Sauce

Add the cooked pasta to the Alfredo sauce and toss gently to coat. Sprinkle in chopped herbs like parsley and dill for brightness. Adjust seasoning with salt and pepper.

Step 6: Assemble and Serve

Plate the Alfredo pasta alongside or underneath the Cajun chicken bites. Finish with more herbs or a fresh crack of black pepper.

How to Serve and Store These Cajun Chicken Bites with Alfredo Twists

Serve hot right off the stove for best flavor. This dish pairs well with crusty bread, a side salad, or roasted veggies. Garnish with extra herbs or a squeeze of lemon juice if you want a citrusy finish.

To store, let the chicken and pasta cool completely before transferring to an airtight container. Refrigerate for up to 4 days. Reheat gently on the stove with a splash of cream or water to loosen the sauce. The chicken can also be frozen for up to a month, but the Alfredo sauce is best enjoyed fresh.

Frequently Asked Questions

What if I don’t have rotini pasta?

Fettuccine, penne, or even spaghetti work just fine. Just aim for a pasta that holds onto sauce well.

Can I use chicken thighs instead of breasts?

Absolutely! Chicken thighs will add even more flavor and tenderness. Just trim excess fat and adjust cooking time slightly.

Is this recipe very spicy?

It depends on your Cajun seasoning. If heat is a concern, choose a mild blend or make your own with less cayenne.

Can I make this dish ahead of time?

Yes. You can prep the chicken and sauce a day in advance. Reheat pasta gently and add fresh herbs before serving.

Can I use milk instead of cream?

Whole milk can work in a pinch, but the sauce will be thinner. For a creamy texture, consider adding a little cream cheese or flour to thicken.

What vegetables go well with this?

Broccoli, asparagus, or spinach make great additions or sides. You can stir them into the Alfredo or serve separately.

Want More Chicken Dinner Ideas?

If you loved these Cajun Chicken Bites with Alfredo Twists, you’ll want to check out more comforting, bold, and easy-to-love dinners:

Creamy Cajun Steak Alfredo for a spiced-up surf-and-turf vibe.
One Pot Creamy Beef and Garlic Butter Pasta when you crave something hearty and fast.
Cheesesteak Tortellini in Rich Provolone Sauce for cheesy indulgence.
Slow Cooker Garlic Butter Beef Bites & Potatoes for a melt-in-your-mouth comfort meal.
Texas Roadhouse Butter Chicken Skillet if you’re all about flavor-forward skillet dinners.

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time: Life with Jam on Pinterest.

And let me know in the comments how yours turned out! Did you go heavy on the spice or keep it mellow? Add veggies? I’d love to hear your twists and tips.

Have a question or want to swap an ingredient? Drop a comment—let’s help each other make every meal count.

Cajun Chicken Bites with Creamy Garlic Herb Alfredo Twists

Author: Jam Scott
Total Time: 30 minutes
Yield: 4 servings

Print Recipe

Description

A sizzling plate of Cajun-spiced chicken bites paired with creamy garlic herb Alfredo pasta—this dish balances bold Southern flavor with comforting creamy richness. Perfect for weeknight meals or special occasions, it comes together quickly and stores well for leftovers too.

Instructions

1. Cube the chicken breasts into bite-sized pieces. Toss them with Cajun seasoning until well coated.

2. Heat olive oil and 1 tablespoon of butter in a large skillet over medium-high heat. Add chicken and cook for 5-7 minutes until golden and fully cooked. Set aside.

3. Boil rotini pasta in salted water according to package directions until al dente. Drain and set aside.

4. In the same skillet used for the chicken, lower the heat to medium. Add the remaining butter and minced garlic. Sauté for 1-2 minutes until fragrant.

5. Pour in the heavy cream. Simmer gently, then stir in the Parmesan cheese. Cook for 3-5 minutes until the sauce thickens slightly.

6. Add the cooked pasta to the sauce. Toss to coat well. Stir in chopped parsley and dill. Season with salt and pepper to taste.

7. Plate the creamy pasta and top with the Cajun chicken bites. Garnish with extra herbs and serve hot.