Rich, creamy, spicy, and utterly comforting, this Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta is everything your dinner dreams are made of. It’s the perfect balance of bold Cajun flavor, smooth Alfredo creaminess, and cheesy indulgence, all wrapped around perfectly cooked rotini pasta.
This dish is weeknight-friendly yet impressive enough for guests. Whether you’re serving it on a chilly evening or just craving something soul-warming and cheesy, this pasta is a guaranteed hit. It’s like a flavor-packed hug in a bowl.
What Kind of Pasta Should I Use?
The twisty shape of rotini is key for this dish because it grabs onto the cheesy, meaty sauce in every nook and cranny. Fusilli or even penne would work in a pinch, but rotini truly shines here. If you’re feeling adventurous, try a spinach or tomato rotini for an added pop of flavor and color.
Ingredients for the Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
Rotini Pasta: Its corkscrew shape is ideal for holding onto thick sauces.
Ground Beef: Provides a hearty base with meaty richness that pairs beautifully with Cajun seasoning.
Cajun Seasoning: Brings a spicy, smoky kick that defines the entire flavor profile.
Garlic: Adds bold aromatic depth to both the beef and sauce.
Velveeta Cheese: Melts into a creamy, velvety sauce that clings to every bite.
Alfredo Sauce: Balances the spice with creamy smoothness and complements the cheese.
Butter: Adds richness and helps sauté the garlic to golden perfection.
Fresh Parsley (optional): A sprinkle of green for a fresh finish and contrast.
Grated Parmesan (optional): For those who want an extra cheesy layer on top.


How To Make the Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
Step 1: Boil the Pasta
Bring a large pot of salted water to a boil and cook the rotini pasta until al dente. Drain and set aside.
Step 2: Brown the Beef
In a large skillet over medium heat, cook the ground beef until it’s no longer pink. Drain excess grease and return to heat.
Step 3: Add Garlic and Cajun Flavor
Add butter and minced garlic to the beef. Sauté until fragrant, about 1-2 minutes. Sprinkle in Cajun seasoning and stir to coat evenly.
Step 4: Create the Cheesy Sauce
Lower the heat to medium-low. Stir in Alfredo sauce and cubed Velveeta cheese. Continue stirring until the cheese is fully melted and the sauce is smooth and creamy.
Step 5: Combine with Pasta
Add the cooked rotini to the skillet and gently fold everything together until the pasta is fully coated with the sauce.
Step 6: Garnish and Serve
Plate the pasta and garnish with freshly chopped parsley and a sprinkle of grated Parmesan if desired. Serve hot.
Serving and Storing Cheesy Garlic Twisted Pasta
Serve this dish hot right from the pan—it’s comfort food at its finest. It pairs well with a crisp green salad or a slice of crusty garlic bread.
To store leftovers, place them in an airtight container and refrigerate for up to 3 days. Reheat on the stovetop or microwave, adding a splash of milk or cream to bring the sauce back to life.
Frequently Asked Questions
How spicy is Cajun seasoning?
It has a kick, but you can adjust the heat level by adding more or less, or using a mild blend.
Can I substitute the ground beef?
Absolutely! Ground turkey, sausage, or even a meatless option like mushrooms or lentils can work.
Can I make this ahead of time?
Yes! Prepare everything, then reheat just before serving. It stores and reheats well.
Can I use homemade Alfredo sauce?
Definitely. A homemade sauce will elevate the flavor even more.
What’s a good side dish?
Think garlic bread, roasted veggies, or even a simple Caesar salad.
Can I freeze this dish?
Yes, though the texture of the sauce may change slightly. Use freezer-safe containers and thaw before reheating.
Want More Pasta Ideas with a Twist?
If you love this Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta, check out these savory favorites:
- Creamy Garlic Parmesan Tortellini with Sausage and Broccoli – a cozy mix of creamy and savory.
- Cheesesteak Tortellini in Rich Provolone Sauce – hearty and ultra cheesy.
- Red Pepper Rigatoni: A Creamy Bold Pasta Delight – perfect for those who like a little heat.
- One Pot Creamy Beef and Garlic Butter Pasta – effortless and comforting.
- Creamy Cheesy Garlic Butter Rigatoni with Savory Beef – rich and family-approved.
Save This Pin + Share Your Results
📌 Save this recipe to your Pinterest comfort food board so you can revisit it anytime:
Follow my Pinterest for daily recipes ➝ Life with Jam
And when you try it, I’d love to hear what you think! Did you make it extra spicy? Swap in a different protein? Leave a comment and let’s chat—your tips help others, too!


Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
- Total Time: 30 minutes
- Yield: 4 servings
Description
This creamy, cheesy, and spicy pasta dish combines twisted rotini pasta with Cajun-seasoned ground beef, a rich Alfredo Velveeta sauce, and bold garlic flavors. It’s a perfect comfort meal that’s easy to prepare and guaranteed to impress.
Ingredients
12 oz rotini pasta
1 lb ground beef
2 teaspoons Cajun seasoning
3 cloves garlic, minced
2 tablespoons butter
1 cup Alfredo sauce
8 oz Velveeta cheese, cubed
2 tablespoons chopped parsley (optional)
1/4 cup grated Parmesan cheese (optional)
Instructions
1. Bring a large pot of salted water to a boil. Cook the rotini until al dente, then drain and set aside.
2. In a large skillet, brown the ground beef over medium heat until fully cooked. Drain any excess fat.
3. Add butter and minced garlic to the skillet with the beef. Cook for 1–2 minutes until garlic is fragrant.
4. Sprinkle Cajun seasoning over the beef and stir to evenly coat.
5. Lower the heat and stir in Alfredo sauce and Velveeta cubes. Stir continuously until the cheese melts and the sauce is creamy.
6. Add the cooked pasta to the sauce. Toss until well coated.
7. Serve hot, garnished with chopped parsley and Parmesan if desired.
Notes
If you want a milder flavor, use half the Cajun seasoning and add more to taste after cooking.
For an extra-cheesy version, stir in a handful of shredded mozzarella before serving.
To reheat, add a splash of milk or cream to revive the sauce and prevent it from drying out.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Category: Pasta
- Method: Stovetop
- Cuisine: American Cajun Fusion
Nutrition
- Serving Size: 1¼ cups
- Calories: 655
- Sugar: 4g
- Sodium: 1180mg
- Fat: 38g
- Saturated Fat: 19g
- Unsaturated Fat: 15g
- Trans Fat: 1g
- Carbohydrates: 44g
- Fiber: 2g
- Protein: 32g
- Cholesterol: 115mg
Keywords: Cajun pasta, cheesy beef pasta, Alfredo Velveeta, garlic pasta, quick dinner
