This Wholesome Chicken Broccoli Alfredo Bake is the kind of weeknight comfort food that wraps you up like a warm blanket. Creamy Alfredo sauce clings to tender pasta, golden chunks of chicken, and perfectly roasted broccoli, then it’s all baked to bubbly, cheesy perfection. It tastes like something you’d order at a cozy Italian restaurant, but it’s made easily in your own kitchen—and yes, it reheats like a dream.

Whether you’re looking for a meal prep favorite, a family-style dinner, or a freezer-friendly bake that comes through on busy nights, this dish checks every box. The blend of roasted vegetables, lean protein, and a creamy, cheesy sauce delivers satisfaction in every bite without feeling too heavy. Add a crisp green salad or some garlic bread and you’ve got dinner done.

What Kind of Alfredo Sauce Should I Use?

You can absolutely use your favorite jarred Alfredo sauce for a quick shortcut, but if you have a few extra minutes, homemade Alfredo is a game changer. Made with butter, heavy cream, garlic, and freshly grated Parmesan, it adds richness and depth that store-bought versions just can’t match. Look for a thick sauce that clings to the pasta well and doesn’t get watery in the oven.

Ingredients for the Wholesome Chicken Broccoli Alfredo Bake

Chicken breast: Lean and protein-packed, chicken is the heart of this dish. Cut it into bite-sized cubes for even cooking.

Broccoli florets: Fresh broccoli roasts up beautifully and adds a pop of color and crunch. You can use frozen in a pinch—just thaw and pat dry first.

Pasta (penne or rigatoni): These sturdy shapes hold onto the creamy sauce and bake up perfectly without getting mushy.

Alfredo sauce: Homemade or store-bought, this creamy sauce is what brings everything together. Rich and garlicky is the goal.

Mozzarella cheese: Adds that stretchy, melty layer on top that makes each bite extra satisfying.

Parmesan cheese: For salty depth and that irresistible cheesy crust.

Olive oil, salt, pepper, garlic powder, and Italian seasoning: These pantry staples enhance the flavors of your chicken and vegetables while roasting.

How To Make the Wholesome Chicken Broccoli Alfredo Bake

Step 1: Roast the Broccoli and Chicken

Preheat your oven to 400°F (200°C). On a large baking sheet, toss broccoli florets and chicken cubes with olive oil, salt, pepper, garlic powder, and Italian seasoning. Spread them out evenly and roast for 20-25 minutes, or until the chicken is fully cooked and the broccoli is just starting to crisp at the edges.

Step 2: Cook the Pasta

While the broccoli and chicken roast, bring a large pot of salted water to a boil. Cook your pasta according to the package directions until al dente. Drain and set aside.

Step 3: Mix It All Together

In a large mixing bowl, combine the cooked pasta, roasted chicken and broccoli, Alfredo sauce, and half of the Parmesan cheese. Stir until everything is evenly coated in the creamy sauce.

Step 4: Assemble and Bake

Transfer the pasta mixture into a greased 9×13-inch baking dish. Sprinkle the top with mozzarella cheese and the remaining Parmesan.

Step 5: Bake Until Bubbly

Bake at 375°F (190°C) for 20-25 minutes, or until the cheese is melted and golden brown on top. Let it rest for 5-10 minutes before serving.

How to Serve and Store This Chicken Broccoli Alfredo Bake

Serve this hearty casserole hot from the oven, ideally with a crisp green salad, roasted veggies, or garlic bread. It’s a crowd-pleaser, so don’t be surprised if your guests ask for seconds.

To store leftovers, let the bake cool completely, then refrigerate in an airtight container for up to 4 days. Reheat in the microwave or covered in the oven until warmed through. This dish also freezes well—just assemble, cover tightly, and freeze before baking. When you’re ready to serve, thaw overnight and bake as directed.

Frequently Asked Questions

How can I make this bake ahead of time?

You can prep everything the night before: roast the chicken and broccoli, cook the pasta, and assemble the casserole. Cover it tightly and refrigerate. When ready to eat, bake as directed.

Can I use rotisserie chicken?

Absolutely! Rotisserie chicken is a great time-saver. Just shred it and mix it in with the other ingredients during assembly.

What other vegetables can I add?

Mushrooms, spinach, or roasted bell peppers work well here. Just make sure to sauté or roast them before mixing them into the bake to avoid extra moisture.

Is this recipe gluten-free?

Not by default, but you can easily make it gluten-free by using gluten-free pasta and double-checking your Alfredo sauce and seasonings.

Can I use a different cheese?

Yes! Gouda, provolone, or even sharp cheddar can be fun alternatives or additions to mozzarella and Parmesan.

How do I make the Alfredo sauce from scratch?

Melt 1/2 cup of butter in a saucepan, add 2 cups of heavy cream and simmer for 5 minutes. Stir in 1 1/2 cups of freshly grated Parmesan cheese and minced garlic to taste. Season with salt and pepper, and whisk until smooth.

Want More Chicken Dinner Ideas?

If you loved this Wholesome Chicken Broccoli Alfredo Bake, try some of these comforting chicken recipes next:

Chicken Crescent Roll Casserole for a flaky, cheesy twist on weeknight dinner.
Sweet Garlic Chicken in the Crockpot when you need slow cooker simplicity.
Creamy Garlic Marry Me Salmon if you’re feeling a bit fancy but still crave creamy goodness.
Melted Mozzarella Ranch Chicken Bombs for a gooey, flavor-packed dinner.
Texas Roadhouse Butter Chicken Skillet when you want skillet-to-table ease with bold flavor.

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out. Did you add mushrooms or a different pasta? Maybe swap the chicken for turkey?

I love hearing how you customize these meals to fit your family. For even more cozy, cheesy dinner inspiration, check out my daily updates on Pinterest @hallarecipes.

Wholesome Chicken Broccoli Alfredo Bake

Author: Jam Scott
Total Time: 1 hour 5 minutes
Yield: 6 servings

Print Recipe

Description

This creamy, cheesy Chicken Broccoli Alfredo Bake brings together roasted chicken, crisp-tender broccoli, and pasta all smothered in rich Alfredo sauce and topped with melty mozzarella. It’s a family favorite that’s easy to prep ahead and freezes beautifully.

Instructions

1. Preheat oven to 400°F (200°C). Line a baking sheet with parchment paper.

2. Toss broccoli florets and cubed chicken with olive oil, garlic powder, Italian seasoning, salt, and pepper. Spread evenly on baking sheet. Roast for 20–25 minutes until chicken is cooked and broccoli edges are crisp.

3. Meanwhile, boil pasta in salted water until al dente. Drain and set aside.

4. In a large bowl, combine cooked pasta, roasted chicken and broccoli, Alfredo sauce, and half the Parmesan. Mix well.

5. Pour mixture into a greased 9×13-inch baking dish. Top with mozzarella and remaining Parmesan.

6. Bake at 375°F (190°C) for 20–25 minutes, until top is golden and bubbly.

7. Let rest for 5–10 minutes before serving.